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Botox, Xeomin, Dysport and Letybo: Which Neuromodulator is best for you?

Writer: Tanya MenonTanya Menon



If you're considering aesthetic treatments to smooth fine lines and wrinkles, you've probably come across several neuromodulators, including Botox, Xeomin, Dysport, and Letybo.


Certain brands seem to blend with their specific use that they almost represent the entire field or industry they belong to. Take Botox as an example of this occurrence, in the world of cosmetics and beauty treatments.


Many are familiar, with Botox. It's a type of injectable containing botulinum toxin type A known for its wrinkle smoothing effects by relaxing muscles through nerve muscle communication disruption. These injections are commonly employed to ease the tension, in the muscles between the eyebrows, forehead wrinkles and lines and around the eyes.


Botulinum toxin comes from a bacterium called Clostridium botulinum. It’s a bacterium that creates eight different types of botulinum toxin. Typ A is one of the most powerful of these and is the only Botulinum toxin currently in cosmetic use.


How do you know which injectable to get? Are they actually different from each other or is it a marketing strategy?


The main difference in across Botox, Xeomin, Dysport, and Letybo relates to the presence or absence of accessory proteins in the formula. Here's a comparison of each product’s additives and how they can impact effectiveness and suitability for different clients:


Botox (Allergan) contains botulinum toxin type A with accessory proteins. These proteins help stabilize the botulinum toxin, potentially aiding in its effectiveness. The accessory proteins may offer some clients added stability, potentially leading to consistent, predictable results. However, in some cases, long-term use can lead to antibody formation. However, it is rare.


Dysport (Galderma) Dysport also contains botulinum toxin type A with accessory proteins. However, Dysport’s formula is designed for more diffusion. It is more diffused than Botox.


Xeomin (Merz) is known as the "pure botulinum toxin type A"" without any accessory proteins. It relies on the active botulinum toxin alone for results. However, it has a limited stability without accessory proteins. Limited stability in botulinum toxins means that they are prone to degradation and can lose effectiveness if not stored or handled correctly. Xeomin is a good option for those who developed resistance to other neuromodulators.


Letybo (Croma Australia) is a newer product by South Korean Brand, made specifically for aesthetic uses. It’s branded as a more affordable option designed exclusively for treating wrinkles. Priced lower than Botox, Dysport and Xeomin making it a budget-friendly option. It contains accessory proteins as Botox and Dysport. It is specifically designed for cosmetic treatment rather than therapeutic applications. It works similarly to Botox in effectiveness and duration.


Final Thoughts

Choosing between these neuromodulators comes down to your unique goals, budget, and treatment area. While Botox remains a trusted favorite, Dysport’s quicker onset, Xeomin’s “naked” formula, and Letybo’s affordability each offer valuable benefits. Consulting with an experienced provider is key to finding the option that best suits your needs.


If you're interested in learning more about these treatments or want to discuss the best choice for you, Yasmine's Aesthetics offers personalized consultations. Mobile service is available at Yasmine's Aesthetics for an additional fee, providing the convenience of receiving treatments in the comfort of your home.





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